Malaria is a parasitic disease caused by plasmodium parasite, whose vector is mosquitoes. Plasmodium infects the red blood cells. Malaria accounts to nearly half million deaths a year with sub-Saharan Africa registering high percentage of deaths.
In the study carried out at University of Nottingham’s School of Life Sciences and published in the journal PLoS Pathogens, the parasite has been found to have special type of protein called Cyclin. Cylin are proteins involved in cell division that signals the passage from one stage of cell division to the next as the cell proliferates. This is important in multiplication of the parasites as they infect more cells. Compared to other Cyclin proteins found in other species e.g. human beings, yeast and plants, the Plasmodium Cyclin have been found to cause the parasite to divide more quickly hence responsible for rampart growth and infection of blood cells by the parasite.
Three genes have been identified in the plasmodium that code for this special type of Cyclins. Discerning the gene interactions(working out the intrinsic properties of the this Cyclin coded by the three genes) in the parasite will give insights into development of better therapeutics and hence eradication of Malaria.
Kadcyla, is a life-extending drug for breast cancer patients (Women) and it also improves the chronic health condition of an individual. Unfortunately, this drug will no longer be offered routinely within NHS in Wale and England because it is highly expensive to most users, says a watchdog. As a result, Cancer Drugs Fund will be the only source where England Women will now be able to access the Kadcyla drug. According to draft NICE guidelines, the tag price per patient at full cost is 90,000 Euros, which is very high to widen access. In addition, Roche, who is the manufacturer, was criticized by NICE for making it less affordable. Roche, however, claimed that a resolution is possible as discussions are still in progress.
Women suffering from incurable disease are recommended to use Kadcyla which can add up to seven months of life. Moreover, the drug is used to treat individuals with breast cancer of HER2-positive that has pread to the rest parts of the body and cannot be surgically removed. Recently, Roche together with NHS England came into an agreement for a significant price discount so as to maintain the drug in Cancer Drugs Fund- the government’s special fund established to help individuals in England access expensive cancer drugs which are not routinely available in NHS.
A recent scientific study related to sugar intake of young children was conducted by a group of scientists, and this study was funded by the National Institutes of Health. It was found out from this study that in just 10 days, young children who suffer from obesity can experience some improvements on their cholesterol count, blood pressure and many others. by simply minimizing their sugar consumption.
The truth is, the kinds of sugar that can be very harmful not only to the younger children out there, but also for adults are those that can be acquired from the manufactured products such as candies. The worse part is, overconsumption of added sugar can lead to metabolic illnesses such as Type 2 Diabetes. The scientists from this particular study also found out that even without trying to lower down the current calorie counts of the children, they can still feel great improvements on their health condition by just taking away the added sugar on their daily diet.
A recent mental health-related study was conducted by the Department of Health and Mental Hygiene of New York City, and it was found out that great percentage of the city’s 8.4 million population is suffering from mental-related issues. When put it in a ratio, 1 out of 5 residents in New York City is suffering from psychological disorders. Some of these psychological disorders can be due to depression, suicidal thoughts, and drug abuse.
The local government of New York City was extremely alarmed with this horrible condition, which is why city mayor Bill de Blasio and his colleagues have come up with an excellent mental health plan as an effective solution for this. Such plan is designed in order to treat and prevent psychological issues from occurring. This plan is called the “NYC Thrive”. The formal launching of this mental health plan will take place on the last day of November 2015. Hopefully, it will be effective enough in lessening the higher cases of mental illnesses in the city.
Recent studies are finding new technologies aid those interested in staying fit. Those who have elected to try out options like the Fitbit have found one of the benefits is a reduction in time spent sitting or in a resting position. Electronically monitoring their movements helps those using these devices to assess their movements, and daily fitness routines, easily and effectively.
Lack of Mobility a Health Risk
As the rate of obesity has tripled in the last few decades health and fitness experts have stressed the dangers of sitting, or being at rest for hours throughout the day. Last year results of studies found that Americans sit for almost 8 hours a day on average and this contributes to obesity. For those who work at desk jobs this is an issue that’s difficult to resolve. Those who spend more time on their feet ,or moving around are found to have a lower body mass index than those who seldom move about. Spending an hour or more a day exercising can help with lowering the body mass and over body fat percentage, but researchers found it’s difficult for the average person to gauge time spent moving or walking during the day.
Getting Out of the Chair
Those looking into the problem of remaining in a resting position for long periods of time recommend standing while talking on the phone, standing while gaming or watching television, and standing up every few minutes once an hour. Developing these habits are thought to offset the average inactive lifestyle that can lead to obesity. In response to this data from health experts many workplaces have instituted policy changes such as allowing employees to stand or move about, rather than constantly sitting. Some schools are also following this trend, allowing students to stand or move about classrooms more frequently during the day.
In recent months, researchers in the U.S. are seeing an encouraging change in national statistics regarding time spent sitting down. Many younger Americans, between the ages of 18 to 35 are using electronic monitoring devices and apps to monitor their movements. This monitoring gives users the ability to see the exact amount of time per day spent sitting, standing, or moving. Since accessing the amount of time spent sitting down is difficult, and time consuming, app users find this method gives them the opportunity to remain alert to their need to stand or walk with less conscious effort.